[(3,5-difluorophenyl)amino](oxo)acetic acid - Names and Identifiers
[(3,5-difluorophenyl)amino](oxo)acetic acid - Physico-chemical Properties
Molecular Formula | C8H5F2NO3
|
Molar Mass | 201.13 |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD11053976 |
[(3,5-difluorophenyl)amino](oxo)acetic acid - Introduction
[(3,5-difluorophenyl) amino] (oxo) acetic acid, also known as [(3,5-difluorophenyl) amino] (oxo) acetic acid, is an organic compound. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Chemical formula: C8H6F2NO3
-Molecular weight: 209.14g/mol
-Appearance: White Crystal
-Melting point: 140-143°C
-Solubility: Limited solubility in water, soluble in organic solvents such as ether and dichloromethane
-Chemical properties: It is an acidic compound that can react with alkali to form salt.
Use:
- [(3,5-difluorophenyl) amino] (oxo) acetic acid is used as an important intermediate in organic synthesis.
-It can be used as a raw material in drug synthesis and used to synthesize many drugs and biologically active compounds.
Preparation Method:
The preparation of [(3,5-difluorophenyl) amino] (oxo) acetic acid can be carried out by the following steps:
1.3,5-difluoronitrobenzene and dimethyl malonate are reacted in the presence of cuprous iodide to obtain 3,5-difluorophenyl methylnitroacetone.
2. reduce 3,5-difluorophenyl methylnitroacetone to [(3,5-difluorophenyl) amino] acetic acid.
3. Oxidation of [(3,5-difluorophenyl) amino] acetic acid to [(3,5-difluorophenyl) amino] (oxo) acetic acid.
Safety Information:
[(3,5-difluorophenyl) amino] (oxo) acetic acid is a chemical, and the following safety precautions should be noted:
-It is a corrosive chemical that can cause irritation when in contact with skin and eyes.
-Wear appropriate personal protective equipment, including lab gloves, goggles and lab coats.
-During storage and handling, observe relevant safety procedures and keep away from ignition and flammable materials.
-If inhaled or taken by mistake, seek medical attention immediately. If contact occurs, rinse skin or eyes immediately with plenty of water.
Please note that the use of chemicals should follow the correct laboratory procedures and follow safety guidelines to ensure safety and effectiveness.
Last Update:2024-04-09 15:18:09